Wednesday, August 23, 2017
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smoking

No Smoker Left Behind: Helping All Australians Quit

A new discussion paper, published today in theMedical Journal of Australia, highlights the need for more comprehensive research and focus on priority groups more...
menopause, leukemia, Sarcoma, neurodegenerative disorders, menopause, autism, Brain-gut-microbiota, Intestinal Inflammation, Parkinson’s disease, Gonorrhea, sclerosis, mammalian, bowel syndrome, pregnancy, cancer, zika virus, HIV, immunotherapy, glioblastoma, stem cells, Metabolic proteins, HIV, protein, prostate cancer, autism, heart failure, DNA, autism disorders

For Post-Menopausal Women, Vaginal Estrogens Do Not Raise Risk of Cancer,...

Findings Women who have gone through menopause and who have been using a vaginal form of estrogen therapy do not have a higher risk of...
cardiovascular disease

Ozone Pollution Connected to Cardiovascular Health

Exposure to ozone, long associated with impaired lung function, is also connected to health changes that can cause cardiovascular disease such as heart attack,...
genes

Common Strength ‘Genes’ Identified for First Time

The very large number of individuals participating in UK Biobank provides a powerful resource for identifying genes involved in complex traits such as muscle...
heartvideo

Your Own Virtual Heart for Non-invasive Heart Diagnostics

One day, a virtual version of your own heart pumping may help doctors diagnose heart disease and determine the best treatment for you, without...
Botryllus schlosseri

Star Power

At first glance, Botryllus schlosseri is pretty nondescript. The small, transparent marine organism, abundant along California’s coast, spends its life colonizing submerged surfaces — boats,...
immune cells, drug development, Diabetes, Antibiotic, hydrogen generation, chronic obstructive pulmonary disease, malaria, photosynthesis, kidney failure, Brain tumours, mental health, blood cancer, cancer, dementia, cancer treatment, antibiotic resistance, blood vessel leakage, quantum simulations, atrial fibrillation, batteries, goiter treatment, terahertz radiation, organic materials , Guild of European Research Intensive Universities, gene copies, social anxiety, blue light screens, ‘Our hope is that these findings will make it possible to discover a way to selectively inhibit the TGF-beta signals that stimulate tumour development without knocking out the signals that inhibit tumour development, and that this can eventually be used in the fight against cancer,’ says Eleftheria Vasilaki, postdoctoral researcher at Ludwig Institute for Cancer Research at Uppsala University and lead author of the study. TGF-beta regulates cell growth and specialisation, in particular during foetal development. In the context of tumour development, TGF-beta has a complicated role. Initially, it inhibits tumour formation because it inhibits cell division and stimulates cell death. At a late stage of tumour development, however, TGF-beta stimulates proliferation and metastasis of tumour cells and thereby accelerates tumour formation. TGF-beta’s signalling mechanisms and role in tumour development have been studied at the Ludwig Institute for Cancer Research at Uppsala University for the past 30 years. Recent discoveries at the Institute, now published in the current study in Science Signaling, explain part of the mechanism by which TGF-beta switches from suppressing to enhancing tumour development. Uppsala researchers, in collaboration with a Japanese research team, discovered that TGF-beta along with the oncoprotein Ras, which is often activated in tumours, affects members of the p53 family. The p53 protein plays a key role in regulating tumour development and is often altered – mutated – in tumours. TGF-beta and Ras suppress the effect of mutated p53, thereby enhancing the effect of another member of the p53 family, namely delta-Np63, which in turn stimulates tumour development and metastasis.

Early COPD Diagnosis Could save Billions of Kronor

The new findings reported in Visby thus indicate that, over a two-year period, early COPD diagnosis could save the public purse approximately SEK 25,000...
stroke and dementiavideo

Daily Consumption of Sodas, Fruit Juices and Artificially Sweetened Sodas Affect...

Data from the Framingham Heart Study (FHS) has shown that people who more frequently consume sugary beverages such as sodas and fruit juices are...
heart attacks

Ban on Trans Fats in Diet May Reduce Heart Attacks and...

People living in areas that restrict trans fats in foods had fewer hospitalizations for heart attack and stroke compared to residents in areas without...
exercise

Exercise as Medicine: What’s the Right Dose When Taken with a...

Researchers continue to gather evidence that exercise can serve as a supplement to, or even a replacement for, drugs in their efforts to combat...
cardiovascular disease

Moderate Drinking Linked to Lower Risk of Some – but Not...

This doesn’t mean that it is advisable for individuals to take up drinking as a means of lowering their cardiovascular risk. There are other,...
cholesterol

Study Suggests New Drug Alongside Statins Can Significantly Cut Cholesterol

In a trial of more than 27,000 patients, researchers found that taking monthly or twice-monthly injections of the medication, called evolocumab, on top of...
Cocoavideo

Cocoa for Pleasure — and Health?

Yes, we love cocoa in winter, particularly around Valentine’s Day. But does cocoa love us? While you may want to pass the mug, you also...
heart failure

Fatty Acids May Lead to First Heart Failure Treatments

University of Rochester Medical Center will be studying omega-3 fatty acids and their use in preventing and treating a certain type of heart failure. According...
menopause

Women with Early Periods at Increased Risk of Early or Premature...

A large international study has linked early puberty and childlessness with an increased risk of early menopause. Professor Gita Mishra from The University of Queensland...
Depression

Depression as Hard on the Heart as Obesity and Cholesterol

According to the World Health Organisation WHO, 350 million people worldwide are affected by depression.* But the mental state is not all that is...
heart attack

Lowering Cholesterol to ‘Levels of a New-born’ Cuts Heart Attack Risk

Although previous studies have suggested lowering cholesterol levels may be associated with a lower risk of heart attack, recent evidence has questioned whether very...
Smoking

No Safe Level of Smoking: Even Low-intensity Smokers Are at Increased...

People who consistently smoked an average of less than one cigarette per day over their lifetime had a 64 percent higher risk of earlier...
nuts

A Handful of Nuts a Day Cuts the Risk of a...

The analysis of all current studies on nut consumption and disease risk has revealed that 20g a day - equivalent to a handful -...
heart rate

High Rest­ing Heart Rate and Blood Pres­sure Linked to Later Men­tal...

The connections between resting heart rate, blood pressure and psychiatric disorders were studied using register data from more than one million Swedish men. The...