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vascular diseases

Liver Inflammation Raises Cholesterol Levels

Inflammatory processes in the liver lead to elevated cholesterol levels in people with diabetes, thus promoting subsequent vascular diseases. This is the result of...
bone loss

Study Paves the Way to a Novel Treatment for Bone Loss

Experiments with mice conducted at the University of São Paulo (USP) in Ribeirão Preto, Brazil, suggest that inhibiting the action of a protein called...
heart attack

Calcium in Arteries Influences Heart Attack Risk

Patients without calcium buildup in the coronary arteries had significantly lower risk of future heart attack or stroke despite other high risk factors such...
obesity

Gene Therapy via Skin Could Treat Diseases Such as Obesity

A University of Chicago-based research team has overcome challenges that have limited gene therapy and demonstrated how their novel approach with skin transplantation could...
Parkinson’s disease

Diabetes Drug Shows Potential as Disease-modifying Therapy for Parkinson’s Disease

A drug commonly used to treat diabetes may have disease-modifying potential to treat Parkinson’s disease, a new UCL-led study suggests, paving the way for...
immune cells, emotions, solitons, enzyme, schistosomiasis, infrared light, brain cancer, chronic pain, Artificial intelligence, immune response, prostate cancer, pollution mitigation, colony collapse, brain diseases, E. coli, enzyme sirtuin 6

Study: Many Kinds of Happiness Promote Better Health

A new study links the capacity to feel a variety of upbeat emotions to better health. The research suggests people who experience a range of...
diabetes

Attending to Diabetes During Pregnancy

Babies born to mothers who develop diabetes during pregnancy – known as gestational diabetes (GDM) – are shown to have attentional deficiencies as early...
Cerebral Palsy, Invasive pests, chronic disease, Bowel Syndrome, prostate cancer, fertility, bacteria, CO2-driven productivity, Dental plaque, cancer, Lap band surgery, fossils, Breast cancer, contact lenses, platinum, disease resistance, greenhouse gases, wrist fracture, dementia, irritable bowel syndrome, Breast Cancer, mental health, leukemia, pollen, schizophrenia, Smarter brains, cancer cells, cardiovascular, genes, plants, Platypus venom

Everyday Chemicals Linked to Chronic Disease in Men

Chemicals found in everyday plastics materials are linked to cardiovascular disease, type-2 diabetes and high blood pressure in men, according to Adelaide researchers. Researchers from...
diabetes

Healthier Lifestyles for Women with Type 2 Diabetes

Helping women with Type 2 diabetes to undertake a more healthy lifestyle is the aim of a wellness program developed by Griffith University, and...
Gut bacteria

Gut Bacteria Can Help to Predict How the Body Will Respond...

Scientists have found that certain compounds, produced by microbes in the guts of mice, could be used to show which animals are at greater...
Diabetes

Bioengineers Improve Diabetes Monitor’s Versatility, Durability

Researchers at The University of Texas at Dallas are getting more out of the sweat they’ve put into their work on a wearable diagnostic...
Pre-eclampsia

Aspirin Reduces Risk of Pre-eclampsia in Pregnant Women

A trial, led by Professor Kypros Nicolaides, Professor of Foetal Medicine at King’s College London, Dr Liona Poon of King’s College, London withProfessor David...
immune system

Study Uses Child’s Own Immune System Against Type One Diabetes

Eighteen-year-old Grace Long had just been accepted at the renowned United States Naval Academy, with plans to become a nuclear engineering officer. Then, she...
immune cells, drug development, Diabetes, Antibiotic, hydrogen generation, chronic obstructive pulmonary disease, malaria, photosynthesis, kidney failure, Brain tumours, mental health, blood cancer, cancer, dementia, cancer treatment, antibiotic resistance, blood vessel leakage, quantum simulations, atrial fibrillation, batteries, goiter treatment, terahertz radiation, organic materials , Guild of European Research Intensive Universities, gene copies, social anxiety, blue light screens, ‘Our hope is that these findings will make it possible to discover a way to selectively inhibit the TGF-beta signals that stimulate tumour development without knocking out the signals that inhibit tumour development, and that this can eventually be used in the fight against cancer,’ says Eleftheria Vasilaki, postdoctoral researcher at Ludwig Institute for Cancer Research at Uppsala University and lead author of the study. TGF-beta regulates cell growth and specialisation, in particular during foetal development. In the context of tumour development, TGF-beta has a complicated role. Initially, it inhibits tumour formation because it inhibits cell division and stimulates cell death. At a late stage of tumour development, however, TGF-beta stimulates proliferation and metastasis of tumour cells and thereby accelerates tumour formation. TGF-beta’s signalling mechanisms and role in tumour development have been studied at the Ludwig Institute for Cancer Research at Uppsala University for the past 30 years. Recent discoveries at the Institute, now published in the current study in Science Signaling, explain part of the mechanism by which TGF-beta switches from suppressing to enhancing tumour development. Uppsala researchers, in collaboration with a Japanese research team, discovered that TGF-beta along with the oncoprotein Ras, which is often activated in tumours, affects members of the p53 family. The p53 protein plays a key role in regulating tumour development and is often altered – mutated – in tumours. TGF-beta and Ras suppress the effect of mutated p53, thereby enhancing the effect of another member of the p53 family, namely delta-Np63, which in turn stimulates tumour development and metastasis.

New Study: Many Diabetes Patients Produce Some Insulin

Type 1 diabetes, a chronic disease mainly debuting during childhood or adolescence, has previously been considered to result in full loss of the patients’...
Celiac Disease

Infections in Early Life Associated with Increased Risk for Celiac Disease

In previous publications, a team of scientists led by Professor Anette-Gabriele Ziegler had already demonstrated an association between infections in early childhood and the...
data storage, pharmacoscopy, satellite, Ebola vaccine, Diabetes, brain cell, dinosaurs, gut bacteria, bandwidth, forest loss, supercomputer, Zealandia, marine ecosystems, ultrafast X-ray, Ant Navigation, Huntington’s disease, carbon dioxide, wind turbine, Alzheimer’s, climate, flu, body clock, joint pain, hurricane

Finnish Study Reveals Link Between Unemployment and Diabetes

Research, partly supported by the EU-funded DYNAHEALTH project, established that, in the men involved, pre-diabetes was found in 19.2% of those employed, 23.0% who’d...
Diabetes

VUMC Team’s Discovery Could Lead to New Diabetes Treatment

High circulating glucose, the hallmark of diabetes, is linked to the disease’s most serious complications including heart disease, kidney failure, blindness and amputation. Diabetes...
kidney disease, cancer, diabetes, autism, Tourette syndrome

Mass. General Study Finds Potential Mechanism for BCG Vaccine Reversal of...

New data from an FDA-approved clinical trial testing the generic vaccine bacillus Calmette-Guérin (BCG) to reverse advanced type 1 diabetes are being presented at...
immune system, sintering, Melanoma, hydrogen fuel cells, Parkinson’s disease, sleep apnea, parasitic worms, melanoma, climate, wastewater

Mild-to-moderate Obstructive Sleep Apnea Associated with Hypertension, Diabetes

Penn State College of Medicine’s Dr. Alexndros N. Vgontzas, professor of psychiatry, and Dr. Yun Li, postdoctoral scholar, are presenting research at this week’s...
beta cells

Beta Cells under Fire

While type 1 diabetes causes the destruction of the beta cells of the islets of Langerhans in the pancreas and the development of an...