Tuesday, September 18, 2018
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Epithelial ovarian cancer

PARP-1 May be Key to Effectiveness of PARP Inhibitors, and Now...

Penn Medicine researchers have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients...
cancer

Targeting Cancer by Sabotaging the DNA Repair Seesaw

A protein that cancer cells rely on to stave off cell death also helps them regulate DNA repair, researchers at Winship Cancer Institute of...
DNA Repair

Cancer Drug Discovery: Targeting DNA Repair

Standard anticancer treatments, such as chemotherapy, target rapidly dividing cells by damaging their DNA. A newer strategy is to undercut cancer cells' ability to...