Tag: PARP
PARP-1 May be Key to Effectiveness of PARP Inhibitors, and Now...
Penn Medicine researchers have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients...
Targeting Cancer by Sabotaging the DNA Repair Seesaw
A protein that cancer cells rely on to stave off cell death also helps them regulate DNA repair, researchers at Winship Cancer Institute of...
Cancer Drug Discovery: Targeting DNA Repair
Standard anticancer treatments, such as chemotherapy, target rapidly dividing cells by damaging their DNA. A newer strategy is to undercut cancer cells' ability to...