Sunday, November 19, 2017
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aneurysm

Keyhole Surgery More Effective Than Open Surgery for Ruptured Aneurysm

More than 1000 people a year in the UK require emergency surgery to repair a ruptured abdominal aortic aneurysm. Without repair, ruptured aneurysm is...
diabetes

The New Research That Could Transform Diabetes Treatment

In the lead-up to World Diabetes Day 2017, newly appointed Associate Professor Samantha Hocking is determined to challenge the one-size-fits-all approach to treatment. Associate Professor...
type 2 diabetes

Study Reveals How a Very Low Calorie Diet Can Reverse Type...

In a new study, a Yale-led research team uncovers how a very low calorie diet can rapidly reverse type 2 diabetes in animal models....
Polymer nanoagents

​NTU Singapore Scientists Create “Tracking” Nanoagents to Illuminate Very Small Diseased...

Polymer nanoagents that can ‘light up’ tiny areas of diseased tissues that conventional methods fail to detect, have been created by a research team...
wounds

Our Body Clocks Cause Wounds Sustained at Night to Heal More...

A new study has discovered how our body clocks cause wounds, such as cuts and burns, to heal approximately 60% faster if the injury...
breast cancer

UVA Tests Power of Focused Ultrasound, Immunotherapy to Battle Breast Cancer

In its latest pioneering effort to harness the power of focused ultrasound to battle disease, the University of Virginia Health System is examining the...
Pancreatic Cancer

Scientists Link Pancreatic Cancer Survival to Four Genes

Alterations in four main genes are responsible for how long patients survive with pancreatic cancer, according to a new study in Jama Oncology. Before now,...
hip replacement

What is the Most Effective Type of Hip Implant Combination for...

The National Institute for Health Research (NIHR)-funded research also confirms previous knowledge from observational evidence that resurfacing hip replacements and metal-on-metal implants fail more...
intestinal tumours, molecular scissors, disease, genetic, immune cells, drug development, Diabetes, Antibiotic, hydrogen generation, chronic obstructive pulmonary disease, malaria, photosynthesis, kidney failure, Brain tumours, mental health, blood cancer, cancer, dementia, cancer treatment, antibiotic resistance, blood vessel leakage, quantum simulations, atrial fibrillation, batteries, goiter treatment, terahertz radiation, organic materials , Guild of European Research Intensive Universities, gene copies, social anxiety, blue light screens, ‘Our hope is that these findings will make it possible to discover a way to selectively inhibit the TGF-beta signals that stimulate tumour development without knocking out the signals that inhibit tumour development, and that this can eventually be used in the fight against cancer,’ says Eleftheria Vasilaki, postdoctoral researcher at Ludwig Institute for Cancer Research at Uppsala University and lead author of the study. TGF-beta regulates cell growth and specialisation, in particular during foetal development. In the context of tumour development, TGF-beta has a complicated role. Initially, it inhibits tumour formation because it inhibits cell division and stimulates cell death. At a late stage of tumour development, however, TGF-beta stimulates proliferation and metastasis of tumour cells and thereby accelerates tumour formation. TGF-beta’s signalling mechanisms and role in tumour development have been studied at the Ludwig Institute for Cancer Research at Uppsala University for the past 30 years. Recent discoveries at the Institute, now published in the current study in Science Signaling, explain part of the mechanism by which TGF-beta switches from suppressing to enhancing tumour development. Uppsala researchers, in collaboration with a Japanese research team, discovered that TGF-beta along with the oncoprotein Ras, which is often activated in tumours, affects members of the p53 family. The p53 protein plays a key role in regulating tumour development and is often altered – mutated – in tumours. TGF-beta and Ras suppress the effect of mutated p53, thereby enhancing the effect of another member of the p53 family, namely delta-Np63, which in turn stimulates tumour development and metastasis.

New Study may Improve Treatment of Intestinal Tumours

Cancer care guidelines have long stipulated that patients with smaller neuroendocrine intestinal tumours should have surgery as soon as a tumour is detected. Now...
Parkinson’s disease

UVA-Led Study Examines Potential of Sound Waves to Manage Parkinson’s Disease

An initial test to determine if a scalpel-free form of brain surgery can reduce tremor caused by Parkinson’s disease has produced encouraging results. Further...
3D implants

Just-in-Time 3D Implants Set to Transform Tumour Surgery

It is also expected to dramatically improve patient and healthcare outcomes. The five-year project, “Just in time implants”, brings together the Australian Government, RMIT University...
root canal

Antimicrobial Gel Developed at IU School of Dentistry Could Improve Root...

More than 15 million root canals are done each year, according to the American Association of Endodontists. During the procedure, the tooth's pulp and...
proton therapy

Proton Therapy Lowers Treatment Side Effects in Pediatric Head and Neck...

Pediatric patients with head and neck cancer can be treated with proton beam therapy (PBT) instead of traditional photon radiation, and it will result...
foetus

Uterine Bacteria Can Affect the Foetus

According to new research, women can have bacteria in their uteri which may have an impact on foetuses’ immune systems. Until now, the ovaries,...
Pancreatic Cancervideo

Minimally Invasive Robotic Surgery Provides New Option for Pancreatic Cancer Patients

Winship Cancer Institute at Emory Saint Joseph's Hospital has expanded surgical options for pancreatic cancer patients with the recent addition of minimally invasive robotic...
breast implants

Rare Cancer Linked with Breast Implants May Be Underreported, Misunderstood

A rare cancer in patients with breast implants may be on the rise, but not all patients and physicians may be aware of the...
breast cancer

Using Artificial Intelligence to Improve Early Breast Cancer Detection

Every year 40,000 women die from breast cancer in the U.S. alone. When cancers are found early, they can often be cured. Mammograms are...
video

Augmented Tongue Ultrasound for Speech Therapy

For a person with an articulation disorder, speech therapy partly uses repetition exercises: the practitioner qualitatively analyzes the patient's pronunciations and orally explains, using...
robotic surgery

Team Developing Imaging Upgrade for Robotic Surgery

Removing part of a kidney with minimally invasive robotic surgery rather than an entire kidney when operating for smaller tumors is often best for...
optical fiber

A Safe Optical Fiber for Delivering Light and Drugs into the...

A flexible, biodegradable optical fiber that can deliver light into the body for medical applications is the latest work of a collaboration between electrical...