Monday, December 10, 2018
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river blindness, anti-cancer drugs, Heroin vaccine, breast cancer, Scientific Breakthroughs, Parkinson’s disease, malaria vaccine, autism, Antibody, Diabetes, cancer

Some Existing Anti-Cancer Drugs May Act in Part by Targeting RNA

Bolstering the notion that RNA should be considered an important drug-discovery target, scientists at Scripps Research have found that several existing, FDA-approved anti-cancer drugs...
atrial fibrillation

Mobile Health Devices Diagnose Hidden Heart Condition in At-Risk Populations

Wearable mobile health devices improved the rate of diagnosis of a dangerous and often hidden heart condition called atrial fibrillation (AFib), according to a...
malaria and zika virus

A Well-Known Animal Health Drug Could Stop Outbreaks of Malaria and...

Medicines given to household pets to kill fleas and ticks might be effective for preventing outbreaks of malaria, Zika fever and other dangerous insect-borne...
Parkinson's

Researchers Uncover Culprit in Parkinson’s Brain Cell Die-Off

An estimated 10 million people worldwide are living with Parkinson’s disease—an incurable neurodegenerative disorder that leads to an increasing loss of motor control. If we...
cross-coupling

A New Cross-Coupling Simplifies the Synthesis of Drug-Like Molecules

Researchers at The Scripps Research Institute (TSRI) have designed a new molecule-building method that uses sulfones as partners for cross-coupling reactions, or the joining...
depression

New Research Points to Better Way to Treat Depression

Scientists on the Florida campus of The Scripps Research Institute (TSRI) have discovered a new target for treating major depressive disorder, a disease that...
Parkinson's

TSRI Researchers Uncover Culprit in Parkinson’s Brain Cell Die-Off

An estimated 10 million people worldwide are living with Parkinson’s disease—an incurable neurodegenerative disorder that leads to an increasing loss of motor control. If we...
depression

New TSRI Research Points to Better Way to Treat Depression

Scientists on the Florida campus of The Scripps Research Institute (TSRI) have discovered a new target for treating major depressive disorder, a disease that...
Marburg Infections

A Potential Cure for Deadly Marburg Infections

With a mortality rate of up to 88 percent, Marburg virus can rip through a community in days—giving it the same pandemic potential as...
viral outbreaks

TSRI Scientists Receive $15 Million to Study Viral Outbreak Survivors

With a new $15 million grant, scientists at The Scripps Research Institute (TSRI) are gearing up for an in-depth study of survivors of viral...
Microscopic chariots

Microscopic Chariots Deliver Molecules Within Our Cells

On the cellular highway, motor proteins called dyneins rule the road. Dyneins “walk” along structures called microtubules to deliver cellular cargo, such as signaling...
cancer metastasis

TSRI Scientists Take Big Step Toward Stopping Cancer Metastasis

New research from The Scripps Research Institute (TSRI) may give scientists a chance to target tumors before they metastasize. The study, published recently in...
Alcoholism

TSRI Receives $10 Million Grant to Study Effects of Alcohol on...

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) has awarded scientists at The Scripps Research Institute (TSRI) a $10 million grant to study...
mesenchymal stem cells

TSRI Researchers Identify Gene Responsible for Mesenchymal Stem Cells’ Stem-Ness

Many doctors, researchers and patients are eager to take advantage of the promise of stem cell therapies to heal damaged tissues and replace dysfunctional...
river blindness, anti-cancer drugs, Heroin vaccine, breast cancer, Scientific Breakthroughs, Parkinson’s disease, malaria vaccine, autism, Antibody, Diabetes, cancer

Estrogen-Mimicking Compounds in Foods May Reduce Effectiveness of Breast Cancer Treatment

Scientists from The Scripps Research Institute (TSRI) have discovered that two estrogen-mimicking compounds found in many foods appear to potently reverse the effects of...
Marburg virus

TSRI Scientists Discover Workings of First Promising Marburg Virus Treatment

With a mortality rate of up to 88 percent, Marburg virus can rip through a community in days. In 2005, an outbreak of Marburg...
Crohn’s disease

Dysfunctional Gene May Be Culprit in Some Crohn’s Disease Cases

Researchers on the Florida campus of The Scripps Research Institute (TSRI) are studying how immune cells adapt as they enter different tissues—with the goal...
anti-cancer

Blueprints for Anti-Cancer Drugs Discovered in Bacterial Genomes

Scientists on the Florida campus of The Scripps Research Institute (TSRI), who had previously discovered the prostate cancer-killing compound LNM E1, have now brought the family...
drug design

New Structure of Key Protein Holds Clues for Better Drug Design

Scientists at The Scripps Research Institute (TSRI) have peered deep into the heart of a key protein used in drug design and discovered dynamic...
sense of touch

Researchers Get First Complete Look at Protein Behind Sense of Touch

Scientists at The Scripps Research Institute (TSRI) have solved the mystery of the structure of Piezo1, a member of a family of proteins that...