Wednesday, September 18, 2019
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Making Cancer Vulnerable to Immune Attack

A novel screening method developed by a team at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center — using CRISPR-Cas9 genome editing technology to test the function...
Gene-Disease, Chronic Pain, Sorafenib, miscarriage, Sudden Infant Death Syndrome, RSV vaccine, aspirin, multiple sclerosis, HIV therapy, resilient coping, liver fibrosis, chronic diseases, birth risk, Alzheimer’s, Brain, Depression, Myeloma, cardiovascular disease, nervous system, addictions

Blood of SIDS Infants Contains High Levels of Serotonin

Blood samples from infants who died of Sudden Infant Death Syndrome (SIDS) had high levels of serotonin, a chemical that carries signals along and...
blood cells

Closing in on a Breakthrough

Researchers at Boston Children’s Hospital have, for the first time, generated blood-forming stem cells in the lab using pluripotent stem cells, which can make...
kidney diseases

Human Stem Cells Model the Kidney’s Filtration Barrier

The kidney, made up of about a million tiny units that work to filter blood, constantly rids the body of undesired waste products to...

Study Points a Way to Better Implants

Medical devices implanted in the body for drug delivery, sensing, or tissue regeneration usually come under fire from the host’s immune system. Defense cells...

How a Child Made Scientists Think of Cytokines as Knobs Instead...

An unusual case of a rare anemia is opening scientists up to a new way of thinking about how to adapt and employ cytokines,...
brain tumors

New Hope for Children with Brain Tumors

Precision medicine — in which diagnosis and treatments are keyed to the genetic susceptibilities of individual cancers — can play a major role in...

Soft Robot Helps the Heart Beat

Harvard University and Boston Children’s Hospital researchers have developed a customizable soft robot that fits around a heart and helps it beat, potentially opening...
optic nerves

Surprise Target

For more than two decades, researchers have tried to regenerate injured optic nerves using different growth factors or agents that overcome natural growth inhibition....
Stem Cells

Color-Coded Stem Cells

A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders...
myelogenous leukemia

Prospect of shorter treatment and cure for chronic myelogenous leukemia 

Combination of treatments may offer cure without need for long-term treatment
sickle cell disease

Gene Therapy for Sickle Cell Disease Passes Key Preclinical Test

A precision-engineered gene therapy virus, inserted into blood stem cells that are then transplanted, markedly reduced sickle-induced red-cell damage in mice with sickle cell...

New Approach to Severe Bacterial Infections and Sepsis

Bacterial infections that don’t respond to antibiotics are of rising concern, as is sepsis — the immune system’s last-ditch attack on infection that ends...

Sepsis-curing device wins new health care prize

Device that filters blood to prevent organ failure wins MIT Sloan Healthcare Innovations Prize.

No more insulin injections?

Encapsulated pancreatic cells offer possible new diabetes treatment.