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brain cancer

Combination Treatment Targeting Glucose in Advanced Brain Cancer Shows Promising Results...

Findings UCLA scientists have discovered a potential combination treatment for glioblastoma, the deadliest form of brain cancer in adults. The three-year study led by David...
zika virus

Zika Virus Selectively Infects and Kills Glioblastoma Cells in Mice

The Zika virus (ZIKV) may infect and kill a specific type of brain cancer cells while leaving normal adult brain tissue minimally affected, according...
cancer

From Thousands of Suspects, Yale Scientists Ferret out Cancer-causing Genes

A Yale-led team of researchers has identified specific gene combinations that can cause the deadly brain cancer glioblastoma, using new technology that can also...
Glioblastoma

Biomedical Engineering Research Points to a New Strategy for Glioblastoma Treatment

Pre-treating glioblastoma cells with a particular protein molecule  increases the selectivity of a promising treatment for this aggressive form of brain cancer, researchers at...
Glioblastomas

Penn Study Suggests that Combining CAR T Cells with Existing Immunotherapies...

Genetically modified “hunter” T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial...
genome

Study by New York Genome Center and IBM Demonstrates Potential for...

In a study published today in the July 11, 2017 issue ofNeurology® Genetics, an official journal of the American Academy of Neurology, researchers at...
brain cancer

Study: New Approach to Destroying Deadly Brain Tumors

A new strategy for treating brain tumors may extend or save the lives of patients diagnosed with one of the deadliest forms of cancer,...
brain cancervideo

First Spherical Nucleic Acid Drug Injected Into Humans Targets Brain Cancer

The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the...
glioblastoma

Researchers Map Genetic Changes in Glioblastoma as It Progresses, Test Potential...

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have mapped genetic changes that help drive an aggressive tumor as it develops...
Cancer Therapy

Researchers Discover New Combination Brain, Blood Cancer Therapy Strategy

Researchers at the University of Cincinnati (UC) College of Medicine have discovered a new potential strategy to personalize therapy for brain and blood cancers.These findings are reported in...
brain cancervideo

‘A Big Step’: UNC Researchers Use Stem Cells to Treat Brain...

University of North Carolina researchers have made recent breakthroughstoward a treatment for a common and aggressive type of brain cancer using human cells.In less...
glioblastoma

Revolutionary Approach for Treating Glioblastoma Works with Human Cells

In a rapid-fire series of breakthroughs in just under a year, researchers at the University of North Carolina at Chapel Hill have made another...
sperm, brain tumours, Common drugs, diabetes, chronic wounds, magnetism, intestinal tumours, molecular scissors, disease, genetic, immune cells, drug development, Diabetes, Antibiotic, hydrogen generation, chronic obstructive pulmonary disease, malaria, photosynthesis, kidney failure, Brain tumours, mental health, blood cancer, cancer, dementia, cancer treatment, antibiotic resistance, blood vessel leakage, quantum simulations, atrial fibrillation, batteries, goiter treatment, terahertz radiation, organic materials , Guild of European Research Intensive Universities, gene copies, social anxiety, blue light screens, ‘Our hope is that these findings will make it possible to discover a way to selectively inhibit the TGF-beta signals that stimulate tumour development without knocking out the signals that inhibit tumour development, and that this can eventually be used in the fight against cancer,’ says Eleftheria Vasilaki, postdoctoral researcher at Ludwig Institute for Cancer Research at Uppsala University and lead author of the study. TGF-beta regulates cell growth and specialisation, in particular during foetal development. In the context of tumour development, TGF-beta has a complicated role. Initially, it inhibits tumour formation because it inhibits cell division and stimulates cell death. At a late stage of tumour development, however, TGF-beta stimulates proliferation and metastasis of tumour cells and thereby accelerates tumour formation. TGF-beta’s signalling mechanisms and role in tumour development have been studied at the Ludwig Institute for Cancer Research at Uppsala University for the past 30 years. Recent discoveries at the Institute, now published in the current study in Science Signaling, explain part of the mechanism by which TGF-beta switches from suppressing to enhancing tumour development. Uppsala researchers, in collaboration with a Japanese research team, discovered that TGF-beta along with the oncoprotein Ras, which is often activated in tumours, affects members of the p53 family. The p53 protein plays a key role in regulating tumour development and is often altered – mutated – in tumours. TGF-beta and Ras suppress the effect of mutated p53, thereby enhancing the effect of another member of the p53 family, namely delta-Np63, which in turn stimulates tumour development and metastasis.

Brain Tumours’ Origin Affects Their Malignancy and Drug Sensitivity

Glioblastoma is the most common form of primary brain tumour in adults and is essentially lethal. Presently, the development of more effective therapies is...
brain proteins, menopause, leukemia, Sarcoma, neurodegenerative disorders, menopause, autism, Brain-gut-microbiota, Intestinal Inflammation, Parkinson’s disease, Gonorrhea, sclerosis, mammalian, bowel syndrome, pregnancy, cancer, zika virus, HIV, immunotherapy, glioblastoma, stem cells, Metabolic proteins, HIV, protein, prostate cancer, autism, heart failure, DNA, autism disorders

Combination Therapy for Glioblastoma Shows Promising Results in Early-stage Research

Findings UCLA researchers have discovered that combining a vaccine developed at UCLA with other experimental therapies and FDA-approved treatments shows promise for reducing the size...
antibiotic resistance, climate change, stressed liver cells, prostate cancer, Retroviruses, specialised ribosomes, colon cancer, Sleep Loss, brain cell, bacteriophages, drug molecules, protein CD93, antibiotic resistance, antibiotic resistance, cancer, melanoma, anti myeloma, Obsessive-compulsive disorder, paper battery, genetic, Brain tumours, sperm, epigenetic, Diabetes, rheumatoid arthritis, genes, solar power, colorectal cancer, epigenetic , dementia, brain treatments, glioblastoma, bladder cancer, Genetic, tumours metastasise, cultured cells, HIV and MDR-TB, magnetic materials, blood test results, Genetics, brain tumour, sleep, motor skills, Chameleonic, gut microbiota, genes, pollutants, penicillin, brain tumours, aneurysms

Therapy Response in Brain Tumour Cells Is Linked to Disease Prognosis

Glioblastoma is a very aggressive tumour form and affected patients only survive for, on average, approximately a year after diagnosis. Researchers believe that the...
brain organoids

A Traditional Japanese Art Inspires a Futuristic Innovation: Brain ‘Organoids’

The ancient Japanese art of flower arranging was the inspiration for a groundbreaking technique to create tiny “artificial brains” that could be used to...
Nanocapsules

Nanocapsules with Anti-inflammatory Drug Reduce Malignant Brain Tumors in Mice

Drugs designed to treat brain diseases must cross the blood-brain barrier, a selectively permeable mass of tightly packed cells that protects the central nervous...
cancer cells

Predicting Cancer Cells’ Response to Chemotherapy

Many chemotherapy drugs work by damaging cancer cells’ DNA so severely that the cells are forced to commit cellular suicide. However, these drugs don’t...
lattice gauge theories, human liver tissue, Ageing, Gaucher disease, psychiatric disorder, Neuron, deuteron, DNA structure, glioblastoma

Gene Fusions Can Lead to Glioblastoma in Children

Every year, about 60 children and adolescents in Germany are diagnosed with glioblastoma, a very aggressive type of brain cancer, which is still mostly...
cancer drugs

A New Strategy for Choosing Cancer Drugs

Choosing the best treatment for a cancer patient is often an inexact science. Drugs that work well for some patients may not help others,...