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HIV treatmentvideo

New Drug Capsule May Allow Weekly HIV Treatment

Researchers at MIT and Brigham and Women’s Hospital have developed a capsule that can deliver a week’s worth of HIV drugs in a single...
cancer

Cell-Weighing Method Could Help Doctors Choose Cancer Drugs

Doctors have many drugs available to treat multiple myeloma, a type of blood cancer. However, there is no way to predict, by genetic markers...
nanoparticles

CRISPR-Carrying Nanoparticles Edit the Genome

In a new study, MIT researchers have developed nanoparticles that can deliver the CRISPR genome-editing system and specifically modify genes in mice. The team...
blood biopsies

New Techniques Give Blood Biopsies Greater Promise

Researchers at the Broad Institute of MIT and Harvard, the Koch Institute for Integrative Cancer Research at MIT, Dana-Farber Cancer Institute, and Massachusetts General...
cancer cells

Gene Circuit Switches on Inside Cancer Cells, Triggers Immune Attack

Researchers at MIT have developed a synthetic gene circuit that triggers the body’s immune system to attack cancers when it detects signs of the...
flexible sensor

Flexible Sensors can Detect Movement in GI Tract

Researchers at MIT and Brigham and Women’s Hospital have built a flexible sensor that can be rolled up and swallowed. Upon ingestion, the sensor...
lung cancer

New Target for Treating “Undruggable” Lung Cancer

Mutations in the KEAP1 gene could point the way to treating an aggressive form of lung cancer that is driven by “undruggable” mutations in...
brain tumors

Biologists Identify Possible New Strategy for Halting Brain Tumors

MIT biologists have discovered a fundamental mechanism that helps brain tumors called glioblastomas grow aggressively. After blocking this mechanism in mice, the researchers were...
RNA Delivery

Bio-Inspired Approach to RNA Delivery

By delivering strands of genetic material known as messenger RNA (mRNA) into cells, researchers can induce the cells to produce any protein encoded by...
liver transplant

Engineered Liver Tissue Expands after Transplant

Many diseases, including cirrhosis and hepatitis, can lead to liver failure. More than 17,000 Americans suffering from these diseases are now waiting for liver...
drug-resistant bacteria

Antibiotic nanoparticles fight drug-resistant bacteria

Targeted treatment could be used for pneumonia and other bacterial infections.
chromosomes

How Cells Combat Chromosome Imbalance

Most living cells have a defined number of chromosomes: Human cells, for example, have 23 pairs. As cells divide, they can make errors that...
ovarian tumors

Study Offers Guidance for Targeting Residual Ovarian Tumors

Most women diagnosed with ovarian cancer undergo surgery to remove as many of the tumors as possible. However, it is usually impossible to eliminate...
brain implants

Making Brain Implants Smaller Could Prolong Their Lifespan

Many diseases, including Parkinson’s disease, can be treated with electrical stimulation from an electrode implanted in the brain. However, the electrodes can produce scarring,...
lung cancer

Biologists Identify Key Step in Lung Cancer Evolution

Lung adenocarcinoma, an aggressive form of cancer that accounts for about 40 percent of U.S. lung cancer cases, is believed to arise from benign...
colon cancer

New Model Could Speed up Colon Cancer Research

Using the gene-editing system known as CRISPR, MIT researchers have shown in mice that they can generate colon tumors that very closely resemble human...
ingestible electronics

Wireless power could enable ingestible electronics

Small sensors or drug delivery devices could reside in the GI tract indefinitely.
ovarian cancer

Revealing Tiny Ovarian Tumors

Most ovarian cancer is diagnosed at such late stages that patients’ survival rates are poor. However, if the cancer is detected earlier, five-year survival...
implants

Study Points a Way to Better Implants

Medical devices implanted in the body for drug delivery, sensing, or tissue regeneration usually come under fire from the host’s immune system. Defense cells...
tumor cells

Tethered Nanoparticles Make Tumor Cells More Vulnerable

MIT researchers have devised a way to make tumor cells more susceptible to certain types of cancer treatment by coating the cells with nanoparticles...