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Schizophrenia

Boosting Amino Acid Derivative May Be a Treatment for Schizophrenia

Many psychiatric drugs act on the receptors or transporters of certain neurotransmitters in the brain. However, there is a great need for...
quantum particles

Spooky Quantum Particle Pairs Fly Like Weird Curveballs

Curvy baseball pitches have surprising things in common with quantum particles described in a new physics study, though the latter fly much more weirdly.In fact,...
Psychotic Disorders

Sibling Bullying Makes Psychotic Disorders Three Times More Likely

People who were involved in sibling bullying during childhood are up to 3x more likely to develop psychotic disorders such as schizophrenia in...
cerebral cortex, lung cancer, heart attack, Childhood Myopia, autism spectrum disorder, health efforts, Clostridium difficile, movement disorders, autism spectrum disorder, hypertension, Parkinson’s Disease, cancer, Kidney Fibrosis, sarcoma, Seizures, Alzheimer’s disease, Kidney Disease, stress, Lung Disease, cancer, blood type, Viral interference, male infants, premature infants, antibodies, breast cancer, DNA repair protein, COX-2 blocker, Alzheimer’s, isoketal-modified proteins, opioids, ebola, nerve degeneration, neurotransmitter, pulmonary fibrosis, schizophrenia

Investigators Eye New Target for Treating Movement Disorders

Blocking a nerve-cell receptor in part of the brain that coordinates movement could improve the treatment of Parkinson’s disease, dyskinesia and other movement disorders,...
memory

Study: Rhythmic Interactions Between Cortical Layers Underlie Working Memory

Working memory is a sort of “mental sketchpad” that allows you to accomplish everyday tasks such as calling in your hungry family’s takeout order...
Schizophrenia

Rare Forms of ‘Thunder’ Protein May Be Linked to Schizophrenia

Researchers at Johns Hopkins Medicine report they have identified rare genetic variations in a protein called Thorase, which is responsible for breaking down receptors...
hormone

Scientists Create Molecule of Love with Fewer Complications

A new and improved version of the ‘love hormone’ oxytocin has been developed by an international collaboration of scientists, including members of staff from...
oligodendrocyte proteomics

Novel Methodology Increases Resolution in Oligodendrocyte Proteomics

One of the key challenges of proteomics, the study of all proteins expressed by a cell or organism, is managing to distinguish between molecules...
Brain Disorders, Rare Immunodeficiency, Hemorrhagic Fevers, silicone rubber, cardiac valves, immune system, sunlight, Autoimmunity

Tracking Down Genetic Influences on Brain Disorders

Individual differences in gene regulation contribute to the development of numerous multifactorial disorders. Researchers are therefore attempting to clarify the influence of genetic variants...
Schizophrenia

Schizophrenia Originates Early in Pregnancy, “Mini-Brain” Research Suggests

Symptoms of schizophrenia usually appear in adolescence or young adulthood, but new research reveals that the brain disease likely begins very early in development,...
astrocytes

Star-shaped Brain Cells Orchestrate Neural Connections

Brains are made of more than a tangled net of neurons. Star-like cells called astrocytes diligently fill in the gaps between neural nets, each...
Grapevine trunk disease, quantum battery, diabetes, laser, brain disorders, Fertilisers, grapes, elephant , bipolar disorder, sudden infant death syndrome, climate, cancer, bacteria, nutritious, physics, type 1 diabetes, pregnancy complications, plant breeding, obesity

Gene Breakthrough on Lithium Treatment for Bipolar Disorder

Genes linked to schizophrenia in psychiatric patients suffering from bipolar disorder are the reason why such patients don't respond to the "gold standard" treatment...
inflammation, vitamin D deficiency, pollutants, environment sensors, tuberculosis treatment, unconscious brain, short-term memory, vitamin D-deficient, synovial sarcoma, Chronic Fatigue Syndrome, inflammation, global warming, movement in the womb, Zero-G, Chemistry breakthrough, human societies, cancer, dementia, autoimmune disease, malaria, Motor Neuron Disease, vitamin D deficiency, minerals, MetalIntelligence, Oesophageal Cancer, Schizophrenia, lung cancer, cancer, tuberculosis, Blood Pressure, disease-causing bacteria, allergic diseases, osteoporosis, MND and schizophrenia, obesity, lasers, plethora, Cancer stem cell, Autism Spectrum Disorder, motor neurons disease, bone graft, Immune system, eczema

Scientists Identify New Mechanism for the Development of Schizophrenia

Scientists from Trinity and the Royal College of Surgeons in Ireland (RCSI) have discovered that abnormalities of blood vessels in the brain may play a...
sperm, brain tumours, Common drugs, diabetes, chronic wounds, magnetism, intestinal tumours, molecular scissors, disease, genetic, immune cells, drug development, Diabetes, Antibiotic, hydrogen generation, chronic obstructive pulmonary disease, malaria, photosynthesis, kidney failure, Brain tumours, mental health, blood cancer, cancer, dementia, cancer treatment, antibiotic resistance, blood vessel leakage, quantum simulations, atrial fibrillation, batteries, goiter treatment, terahertz radiation, organic materials , Guild of European Research Intensive Universities, gene copies, social anxiety, blue light screens, ‘Our hope is that these findings will make it possible to discover a way to selectively inhibit the TGF-beta signals that stimulate tumour development without knocking out the signals that inhibit tumour development, and that this can eventually be used in the fight against cancer,’ says Eleftheria Vasilaki, postdoctoral researcher at Ludwig Institute for Cancer Research at Uppsala University and lead author of the study. TGF-beta regulates cell growth and specialisation, in particular during foetal development. In the context of tumour development, TGF-beta has a complicated role. Initially, it inhibits tumour formation because it inhibits cell division and stimulates cell death. At a late stage of tumour development, however, TGF-beta stimulates proliferation and metastasis of tumour cells and thereby accelerates tumour formation. TGF-beta’s signalling mechanisms and role in tumour development have been studied at the Ludwig Institute for Cancer Research at Uppsala University for the past 30 years. Recent discoveries at the Institute, now published in the current study in Science Signaling, explain part of the mechanism by which TGF-beta switches from suppressing to enhancing tumour development. Uppsala researchers, in collaboration with a Japanese research team, discovered that TGF-beta along with the oncoprotein Ras, which is often activated in tumours, affects members of the p53 family. The p53 protein plays a key role in regulating tumour development and is often altered – mutated – in tumours. TGF-beta and Ras suppress the effect of mutated p53, thereby enhancing the effect of another member of the p53 family, namely delta-Np63, which in turn stimulates tumour development and metastasis.

​Epigenetic Changes and Disease – What Is the Connection?

The risk of developing our most common diseases depends on inheritance, lifestyle and environment. In recent years, epigenetic changes have also been assumed to...
schizophrenia

Study Associates Schizophrenia with Defective Processing of Messenger RNA in Cells

In the human organism, a single gene can give rise to different proteins according to the needs of the moment and in response to...
neuropsychiatric disorders

How an Unlikely Cellular ‘Antenna’ Can Impair Brain Development

An antenna-like structure on cells, once considered a useless vestige, appears to be important for proper brain development in mammals and when impaired can...
Alzheimer’s disease

Vanderbilt Begins Phase 1 Trials of New Alzheimer’s Drug

A potential new drug for Alzheimer’s disease and schizophrenia developed by Vanderbilt University scientists was administered July 29 to the first volunteer enrolled in...
human brain

Lab-Created Mini-Brains Reveal How Growing Organ Maintains Neuronal Balance

Scientists can now explore in a laboratory dish how the human brain develops by creating organoids — distinct, three-dimensional regions of the brain. In...
schizophrenia

Body Ownership Is Not Impaired in Schizophrenia

Schizophrenia patients often experience an altered sense of self, e.g. as if someone else is controlling their actions. This impairment is described as a...
Schizophrenia

IBM and University of Alberta Publish New Data on Machine Learning...

IBM scientists and the University of Alberta in Edmonton, Canada, have published new data in Nature's partner journal, Schizophrenia1, demonstrating that AI and machine...