Thursday, August 22, 2019
Home Tags Scientific

Tag: scientific

Suicidal Thoughts

CMU, Pitt Brain Imaging Science Identifies Individuals With Suicidal Thoughts

Researchers led by Carnegie Mellon University's Marcel Just and the University of Pittsburgh's David Brent have developed an innovative and promising approach to identify...
wind tunnelvideo

Getting Quicker – More Quickly

The skier buckles her boots, grabs her poles and snaps her goggles into place. She's ready to go – but she’s not on the...
ocean

The Oceans Were Colder than We Thought

According to the methodology widely used by the scientific community, the temperature of the ocean depths 100 million years ago was around 15 degrees...
gut capsule

Fellowship a Tasty Treat for Disease-Busting Gut Capsule

The ingestible capsule uses sensors to measure gases in the intestinal tract that help detect disease and disorders. What’s missing is the ability to...
anti-inflammatory

Little-Known Fruits Contain Powerful Anti-Inflammatory and Anti-Oxidant Agents

Five native Brazilian berries, four of which belong to the genus Eugenia, are just starting to become well-known among scientists but are not yet...
memory device

Research Team Led by NUS Scientists Breaks New Ground in Memory...

An international research team led by scientists from the National University of Singapore (NUS) pioneered the development of a novel thin, organic film that...
self-esteem

Self-Esteem Mapped in the Human Brain

A team of UCL researchers has devised a mathematical equation that can explain how our self-esteem is shaped by what other people think of...
digital memories

New Material for Digital Memories of the Future

The phenomenon can be used for small and flexible digital memories of the future, and for completely new types of solar cells.In an article...
alarm

Alarm Gives Epileptics Peace of Mind

Epileptic seizures occur suddenly and can be life-threatening. But an alarm developed jointly by doctors, a technology company, and researchers at DTU Electrical Engineering...
Parkinson’s

Data and Technology Drive New Approaches to Parkinson’s Care, Research

Complex, multi-system diseases like Parkinson’s have long poised challenges to both scientists and physicians.  University of Rochester Medical Center (URMC) researchers are now reaching...
pollutant

Pollutant Emitted by Biomass Burning Causes DNA Damage and Lung Cell...

When exposed in a laboratory to pollution levels comparable to those found in the atmosphere of the Amazon region during the forest and crop...
sugarcane

Modified Yeast Increases Sugar Output from Energy Sugarcane

Varieties of “energy sugarcane” obtained by crossbreeding the species Saccharum officinarum and Saccharum spontaneum have been grown in Brazil in recent years.More robust and...
Influenza Vaccine

Experts Outline Pathway to a Universal Influenza Vaccine

Scientists and clinicians from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and the California Institute...
fertilizers

Fertilizers Adjust Nitrogen Cycle of Prairie Plants, According to Iowa State...

Excess nitrogen gives an advantage to early season plants in Midwestern prairies, leading to further changes in prairie ecosystems, according to a recently published...
mindfulness and meditation

Mindfulness and Meditation Need More Rigorous Study, Less Hype

Dependable scientific evidence has lagged worrisomely behind the rapid and widespread adoption of mindfulness and meditation for pursuing an array of mental and physical...
video

Project Aims to Sequence All Known Species on Earth

Sequencing the DNA of all known species on Earth in a period of ten years, from microorganisms invisible to the naked eye to the...
cone snail

How the Cone Snail’s Deadly Venom Can Help Us Build Better...

Cone snails have inspired humans for centuries. Coastal communities have often traded their beautiful shells like money and put them in jewelry. Many artists,...
stem cells

Major Rethink Needed on Stem Cells and Regenerative Medicine

UCL researchers are leading a call for a coordinated strategy to reform the management of scientific discoveries and clinical experimentation involving stem cells and...
Zika serotypes

New Zika Serotypes May Emerge, Researcher Warns

Zika virus is mutating so fast in Brazilian patients that different serotypes of the pathogen could appear in the near future, as is already...
sperm, brain tumours, Common drugs, diabetes, chronic wounds, magnetism, intestinal tumours, molecular scissors, disease, genetic, immune cells, drug development, Diabetes, Antibiotic, hydrogen generation, chronic obstructive pulmonary disease, malaria, photosynthesis, kidney failure, Brain tumours, mental health, blood cancer, cancer, dementia, cancer treatment, antibiotic resistance, blood vessel leakage, quantum simulations, atrial fibrillation, batteries, goiter treatment, terahertz radiation, organic materials , Guild of European Research Intensive Universities, gene copies, social anxiety, blue light screens, ‘Our hope is that these findings will make it possible to discover a way to selectively inhibit the TGF-beta signals that stimulate tumour development without knocking out the signals that inhibit tumour development, and that this can eventually be used in the fight against cancer,’ says Eleftheria Vasilaki, postdoctoral researcher at Ludwig Institute for Cancer Research at Uppsala University and lead author of the study. TGF-beta regulates cell growth and specialisation, in particular during foetal development. In the context of tumour development, TGF-beta has a complicated role. Initially, it inhibits tumour formation because it inhibits cell division and stimulates cell death. At a late stage of tumour development, however, TGF-beta stimulates proliferation and metastasis of tumour cells and thereby accelerates tumour formation. TGF-beta’s signalling mechanisms and role in tumour development have been studied at the Ludwig Institute for Cancer Research at Uppsala University for the past 30 years. Recent discoveries at the Institute, now published in the current study in Science Signaling, explain part of the mechanism by which TGF-beta switches from suppressing to enhancing tumour development. Uppsala researchers, in collaboration with a Japanese research team, discovered that TGF-beta along with the oncoprotein Ras, which is often activated in tumours, affects members of the p53 family. The p53 protein plays a key role in regulating tumour development and is often altered – mutated – in tumours. TGF-beta and Ras suppress the effect of mutated p53, thereby enhancing the effect of another member of the p53 family, namely delta-Np63, which in turn stimulates tumour development and metastasis.

Mechanism Behind ‘DNA Scissor’ CRIPSR-Cas9 Further Revealed

In less than a decade, CRISPR-Cas9 has revolutionised biological research. Cas9 makes it possible, for specific purposes, to correct or modify (‘edit’) essentially any...