Wednesday, October 17, 2018
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Drug Research

Machine Learning to Accellerate Drug Research

The development of new drugs is a lengthy and expensive process. It is often only after a long development period that it becomes apparent...
Sugar Metabolism

Sugar Metabolism Controls Intestinal Regeneration

No other tissue in our body has such a high rate of cell renewal as the intestine. Since the intestinal tissue has an enormous...
medulloblastoma

New Approach Uncovers Tumor Promoting Signaling Pathway in Common Children’s Brain...

The "Hopp Children's Cancer Center at the NCT Heidelberg" (KiTZ) is a joint initiative of Heidelberg University Hospital and the German Cancer Research Center...
cancer drug

Cancer Drug – in a Different Way Than Expected

Polo-like kinase 1 (PLK1) is overexpressed in a large number of cancers, especially in fast-growing, chromosome-unstable tumors. The enzyme is involved in cell division:...
brain cancer

Brain Cancer: Typical Mutation in Cancer Cells Stifles Immune Response

The exchange of a single amino acid building block in a metabolic enzyme can lead to cancer. In addition, it can impair the immune...
Sleeping Sickness

Sleeping Sickness: Pathogens Camouflage Themselves with Sugar

It has long been known that the pathogens causing sleeping sickness evade the immune system by exchanging their surface proteins. But now scientists at...
Diabetes

Mechanism of Action of a Diabetes Drug Differs Between Males and...

The number of people with diabetes mellitus is increasing in Germany. It is now estimated that 7 to 8 percent of adults in this...
blood cancer cells

New Technique Makes Blood Cancer Cells Visible for the Immune System

Chronic lymphocytic leukemia (CLL) is the most common type of blood cancer in adults. It can be treated with chemotherapy and oral drugs but...
breast cancer

14 New Breast Cancer Risk Genes Discovered

Many genetic markers associated with the familial breast cancer risk are outside the protein-coding regions of the genome and are likely to regulate the...
aging

Key Molecule of Aging Discovered

Oxidative stress causes cells and entire organisms to age. If reactive oxygen species accumulate, this causes damage to the DNA as well as changes...
malaria

Malaria: Cooperating Antibodies Enhance Immune Response

Each year, an estimated 200 million people contract malaria and approximately 440,000 people succumb to the infectious disease. Although regarded as a tropical disease,...
breast cancer

Breast Cancer: Microproteins Essential for Cancer Growth

In women, breast cancer is the most common cancer. One in eight women suffers from a malignant tumor in her breast during her life....
antibodies

“Universal Antibodies” Disarm Various Pathogens

Bacteria and other microorganisms display structures from sugar molecules on their surfaces. These sugar structures play an important role for immune defense. "They enable...
childhood brain tumors

Genetic Analysis for Certain Childhood Brain Tumors Soon a Standard-Of-Care?

Medulloblastoma is a rare malignant tumor of the cerebellum and occurs predominantly in children. Scientists believe that in many cases hereditary gene defects trigger...
alcohol consumption

Alcohol: Redefined Upper Limit for Low-Risk Consumption

The study, led by Angela M Wood and John Danesh, Cambridge University, compared the drinking habits of 600,000 people from 19 countries worldwide. Scientists...
breast cancer

Breast Cancer Therapy: All Clear for the Heart

Breast cancer is the second most frequent cancer worldwide and the most common cancer in women. About 70,000 women are diagnosed with breast cancer...
Alzheimer’s disease

Blood Test Indicates Risk of Developing Alzheimer’s Disease

There is as yet no cure for Alzheimer's disease. It is often argued that progress in drug research has been hampered by the fact...
Alzheimer’s Disease

Blood Test Indicates Risk of Developing Alzheimer’s Disease

There is as yet no cure for Alzheimer's disease. It is often argued that progress in drug research has been hampered by the fact...
diabetes

Diabetes: Are High Blood Glucose Levels an Effect Rather Than the...

Type 2 diabetes, a form of diabetes with a typical onset in middle or older age, causes severe health complications including elevated risks for...
Pancreatic cancer

Pancreatic Cancer: Gene Duplication Explains Tumor Aggressiveness

Until now, scientists have failed to establish a link between the properties of pancreatic cancer, such as its aggressiveness, and changes, i.e. mutations, in...