Sunday, November 18, 2018
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machine-learning

AI and NMR Spectroscopy Determine Atoms Configuration in Record Time

Many drugs today are produced as powdered solids. But to fully understand how the active ingredients will behave once inside the body, scientists need...
4D-CHAINS

New Software Developed at CEITEC MU Automates NMR Structural Studies

Researchers from CEITEC MU developed a streamlined strategy designed to meet the key objectives of NMR structure determination, that is minimal data collection, least...
drug design

New Structure of Key Protein Holds Clues for Better Drug Design

Scientists at The Scripps Research Institute (TSRI) have peered deep into the heart of a key protein used in drug design and discovered dynamic...
T cells

UMD’s IBBR Awarded NIH Grant to Investigate Body’s T-cell Mechanism of...

A new research initiative by the University of Maryland's Institute for Bioscience and Biotechnology Research (IBBR) and the University of Pittsburgh could help uncover...
HIV

Researchers Discover a “Brake” That Interferes with HIV’s Ability to Infect

Viewed with a microscope, the virus faintly resembles a pineapple—the universal symbol of welcome. But HIV, the virus that causes AIDS, is anything but...
batteries

“Holy Grail” for Batteries: Solid-State Magnesium Battery a Big Step Closer

A team of Department of Energy (DOE) scientists at the Joint Center for Energy Storage Research (JCESR) has discovered the fastest magnesium-ion solid-state conductor,...
cholesterol

Cholesterol Helps Flu Virus Escape Through Host Cell’s Membrane

After a flu virus infects a host cell and hijacks its inner workings to create copies of itself, these copies gather into viral buds...
facial recognition

SMART: Facial Recognition for Molecular Structures

An interdisciplinary team of researchers at the University of California San Diego has developed a method to identify the molecular structures of natural products...
Alzheimervideo

Sharpest Image of Alzheimer’s Fibrils Shows Previously Unknown Details (Science)

The structure reveals how the many single Aβ protein molecules are staggered in layers on top of each other and are arranged into so-called...
cancer treatment

Nucleotide Excision Repair Project Promises Progress in Cancer Treatment Methods

In the EU-funded NER (Structural studies of Nucleotide Excision Repair for drug development targeting protein-DNA interactions) project we set out to resolve the human...
protein

UMass Amherst Biochemists Simulate a Protein-Folding Chaperone’s Functional Dance

Using a combination of computational and experimental techniques, a research team at the University of Massachusetts Amherst led by molecular biologist Lila Gierasch has...
Fluoride

The Science of Fluoride Flipping

So much of what happens inside cells to preserve health or cause disease is so small or time-sensitive that researchers are just now getting...
antibiotics

Structure of Newly Discovered Antibiotics Finally Pinned Down

In 2014, a team from Michigan University discovered two molecules, baulamycins A and B, from the coast of Costa Rica that were very active...
magnetic resonance

Company Innovates by Using Magnetic Resonance to Evaluate Food Quality

The applications and benefits of nuclear magnetic resonance (NMR) in medicine are well known, but the technology is also used in other areas, such...
catalysts

Scientists Can Now Locate Oxygen in the Structure of Catalysts with...

A major new application of Dynamic Nuclear Polarization NMR technology at the U.S. Department of Energy’s Ames Laboratory has led to the ability to...
Infectious Disease

Tackling Infectious Disease — One Protein at a Time

Garry Buchko and his colleagues are at the front line battling some of the most fearsome enemies that humanity has ever known: Tuberculosis. Pneumonia....
infectious disease

Tackling Infectious Disease — One Protein at a Time

Garry Buchko and his colleagues are at the front line battling some of the most fearsome enemies that humanity has ever known: Tuberculosis. Pneumonia....
Amyloids

Chemists Reveal Amyloid Structure

Amyloids are clumps of protein fragments that stick together to form stringy fibrils such as the plaques seen in the brains of Alzheimer’s patients....
immune system

Study Unveils T Cell Signaling Process Central to Immune Response

The immune system cells known as T cells play a central role in the body's ability to fight infections and cancer. For decades, however,...
sleeping sickness

New Therapeutic Strategy Against Sleeping Sickness

A newly developed small molecule selectively kills the pathogen causing sleeping sickness and Chagas disease. Scientists from the Technical University of Munich, the Helmholtz...