Saturday, September 23, 2017
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Liquid Biopsiesvideo

Sound Waves Separate Biological Nanoparticles for ‘Liquid Biopsies’

A prototype device developed by an international team of engineers can sift exceedingly tiny particles from blood samples without having to send samples off...
cancer

New Project Will Develop Light-Activated Molecules to Fight Cancer and Infection

Scientists from Trinity College Dublin and six other countries are leading a €2.5 million Horizon 2020-funded project to optimise the design of molecules that...
lupus

Regular Exercise, Stress Can Both Make a Big Difference in Lupus,...

Waking up in the morning with the joint pain, swelling and stiffness that accompanies lupus doesn’t exactly inspire a workout. But research in mice and...
diagnose disease

Doctors Can Now Predict the Severity of Disease Just by Measuring...

An international team of researchers has found a way to diagnose disease and predict patient outcomes simply by measuring unbelievably small changes in interactions...
olives

Virginia Tech Biochemists Dip into the Health Benefits of Olives and...

The health benefits of olives— and associated natural products such as olive oil—have long been recognized and touted by proponents of the Mediterranean diet. However,...
spin, human nutrition, blockchain

Don’t Believe the Hype – Science Spin Prevalent, Researchers Warn

Researchers from the University’s multidisciplinary Charles Perkins Centreand Faculty of Pharmacy reviewed 35 published academic studies of so-called ‘spin’ in biomedical scientific papers –...
antibiotics

Researchers Break Resistant Bacteria’s Defence Against Antibiotics

Bacteria like staphylococci can cause serious diseases, and today the main form of treatment is antibiotics. However, seeing as staphylococci are naturally resistant to...
smart datavideo

Arjun Shankar: Advancing National Missions Through Smart Data

The field of “Big Data” has exploded in the blink of an eye, growing exponentially into almost every branch of science in just a...
Artificial Intelligencevideo

IBM and MIT to Pursue Joint Research in Artificial Intelligence, Establish...

IBM and MIT today announced that IBM plans to make a 10-year, $240 million investment to create the MIT–IBM Watson AI Lab in partnership...
genetic, immune cells, drug development, Diabetes, Antibiotic, hydrogen generation, chronic obstructive pulmonary disease, malaria, photosynthesis, kidney failure, Brain tumours, mental health, blood cancer, cancer, dementia, cancer treatment, antibiotic resistance, blood vessel leakage, quantum simulations, atrial fibrillation, batteries, goiter treatment, terahertz radiation, organic materials , Guild of European Research Intensive Universities, gene copies, social anxiety, blue light screens, ‘Our hope is that these findings will make it possible to discover a way to selectively inhibit the TGF-beta signals that stimulate tumour development without knocking out the signals that inhibit tumour development, and that this can eventually be used in the fight against cancer,’ says Eleftheria Vasilaki, postdoctoral researcher at Ludwig Institute for Cancer Research at Uppsala University and lead author of the study. TGF-beta regulates cell growth and specialisation, in particular during foetal development. In the context of tumour development, TGF-beta has a complicated role. Initially, it inhibits tumour formation because it inhibits cell division and stimulates cell death. At a late stage of tumour development, however, TGF-beta stimulates proliferation and metastasis of tumour cells and thereby accelerates tumour formation. TGF-beta’s signalling mechanisms and role in tumour development have been studied at the Ludwig Institute for Cancer Research at Uppsala University for the past 30 years. Recent discoveries at the Institute, now published in the current study in Science Signaling, explain part of the mechanism by which TGF-beta switches from suppressing to enhancing tumour development. Uppsala researchers, in collaboration with a Japanese research team, discovered that TGF-beta along with the oncoprotein Ras, which is often activated in tumours, affects members of the p53 family. The p53 protein plays a key role in regulating tumour development and is often altered – mutated – in tumours. TGF-beta and Ras suppress the effect of mutated p53, thereby enhancing the effect of another member of the p53 family, namely delta-Np63, which in turn stimulates tumour development and metastasis.

Genetic Effects Are Influenced by Lifestyle

In the current study, researchers have investigated if genetic effects are influenced by different lifestyle factors such as diet, smoking, socio-economic status, alcohol consumption...
Quantum Pascal

NIST, Industry Partner Aim to Develop ‘Quantum Pascal’ Standard Into Real-World...

In our everyday lives, pressure can mean a looming work deadline, a final exam, or bases loaded in the bottom of the ninth. In...
caterpillars

German Scientists Question Study about Plastic-Eating Caterpillars

In April, the report of plastic bag eating caterpillars caused sensation in worldwide media. The authors around Federica Bertocchini of the University in Santander...
nanopores

Research Shows How DNA Molecules Cross Nanopores

Research presented in a new paper co-authored by Northwestern University associate professor of mechanical engineering Sandip Ghosal sheds new light on how polymers cross...
Finger Millet

First Detailed Decoding of Complex Finger Millet Genome

For many poor farmers in India and Africa, finger millet is a major staple food. The crop species is not only a rich source...
movements

Computers Able to Mimic Unique Movements, Finds Study

A team of researchers has today published the first study to show that each one of us has a unique 'control profile' that can...
improve health care

$46 Million Supports Research Likely to Result in New Therapies, Improve...

Washington University School of Medicine in St. Louis has received a $46 million grant from the National Institutes of Health (NIH) to support research...
pesticides

Extreme Exposure

Although common opinion holds that exposure to pesticides increases adverse birth outcomes, the existing body of scientific evidence is ambiguous. Logistical and ethical barriers...
Magnetometer

NASA Technologist Develops Self-Calibrating, Hybrid Space Magnetometer

They’ve flown on high-profile interplanetary and more modest low-Earth-orbiting missions, but in all cases the ubiquitous fluxgate magnetometers that scientists use to measure the...
computing codesvideo

Big Bang – The Movie

If you have ever had to wait those agonizing minutes in front of a computer for a movie or large file to load, you’ll...
robotsvideo

Robots Can Heal Themselves

Research into soft robots has been underway for some time at the Vrije Universiteit Brussel (VUB). Inspired by the soft tissue from which humans and many...