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CAR T cell therapy

T Cell Biomarker Predicts Which CLL Patients Will Respond to CAR...

Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia (CLL) don’t respond to chimeric antigen receptor (CAR)...
HIV

Gene Therapy Using CAR T Cells Could Provide Long-Term Protection Against...

Findings A UCLA-led research team has created blood-forming stem cells that can carry a gene that allows the body to produce cells that can detect...
immunotherapy system

Researchers Develop a Remote-Controlled Cancer Immunotherapy System

A team of researchers has developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that...
cancer therapy, melanoma, Dry Eye Disease, cancer, Myeloma, Multiple Myeloma, Crohn’s disease, Polycystic Ovary Syndrome, Sleep Deprivation, machine-learning, traumatic brain injury

CAR T, Immunotherapy Bring New Hope for Multiple Myeloma Patients

Two investigational immunotherapy approaches, including chimeric antigen receptor (CAR) T cell therapy, have shown encouraging results in the treatment of multiple myeloma patients who...
blood cancersvideo

New Gene-Altering Treatment Offered for Certain Blood Cancers

Amanda Cashen, MD, examines patient Marie Miceli at Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis. Miceli...
opioid agonist therapy, breast cancer, Pediatric Leukemia, Knee Surgery, Acute Kidney Injury, reproductive disease, diabetes, prostate cancer, ear tumor, tumor, asthma, lung cancer, anti-viral, norovirus, antibiotic

New Cutting-Edge Treatment for Type of Pediatric Leukemia Offered at Monroe...

Monroe Carell Jr. Children’s Hospital at Vanderbilt is part of a select group of health care institutions recently chosen to offer a new FDA-approved...
Leukemia

FDA Approves Personalized Cellular Therapy for Advanced Leukemia Developed by University...

In a landmark decision for the field of cancer immunotherapy, the U.S. Food and Drug Administration (FDA) today approved a personalized cellular therapy developed...
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Mass. General Team Reports First Response of Central Nervous System Tumor...

In a letter to the New England Journal of Medicine, a Massachusetts General Hospital (MGH) research team reports a remarkable treatment response in a...
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Off-the-Shelf T Cell Therapies for Multiple Myeloma

There are currently three main approaches for obtaining therapeutic T cells: the isolation, expansion and reinfusion of tumour-infiltrating lymphocytes (TILs); the ex vivo generation...
Glioblastomas

Penn Study Suggests that Combining CAR T Cells with Existing Immunotherapies...

Genetically modified “hunter” T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial...
cancervideo

The Self-defence Force Awakens

T-cells are the body’s serial killers, patrolling, identifying and destroying infected and cancer cells with remarkable precision and efficiency. Gillian Griffiths An army of cells constantly...
immunotherapy

UNC Lineberger Launches Innovative Cellular Immunotherapy Program

University of North Carolina Lineberger Comprehensive Cancer Center researchers have achieved a major milestone with the launch of two clinical trials testing an experimental...
gene therapy

Successful Cooperation in Gene Therapy

Gene therapy, which is the controlled replacement or repair of defective gene variants that pose a health threat, is one of the highest profile...
Immunotherapy

Immunotherapy: Harnessing Cellular Systems to Fight Deadly Diseases

Four decades ago, researchers at the University of Wisconsin School of Medicine and Public Health had the right idea—to pursue a theory that they...
cancer treatment

New Approach to Cancer Treatment Carries Success with Caveat

In people with chronic infections or cancer, disease-fighting T cells tend to behave like an overworked militia — wheezing, ill-prepared, tentative, in a state...
cancersvideo

Special T Cells That Target Solid Tumors Offer Potential Treatment for...

Adoptive cell-therapies, in which a patient’s own immune cells are used to recognize and target tumors, have shown breakthrough results for patients with certain...
chemotherapy

Chemotherapy and Exercise: The Right Dose of Workout Helps Side Effects

Researchers at the University of Rochester Wilmot Cancer Institute discovered something simple and inexpensive to reduce neuropathy in hands and feet due to chemotherapy—exercise. The study, involving more...
T-cell cancer treatment

Purdue research may expand engineered T-cell cancer treatment

Purdue University researchers may have figured out a way to call off a cancer cell assassin that sometimes goes rogue and assign it a...
video

Wilmot Embarks on “first real big test” of Immunotherapy for Lymphoma

UR Medicine’s Wilmot Cancer Institute is part of a national clinical trial for an innovative new therapy that involves engineering a patient’s own immune...