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cystic fibrosis

Scientists Solve 3-D Structure of CF Protein in Active, Inactive States

Scientists at the UNC School of Medicine in collaboration with researchers at Oregon Health & Science University have resolved the three-dimensional molecular structure of...
cystic fibrosis

New Simple Test Could Help Cystic Fibrosis Patients Find Best Treatment

Several cutting-edge treatments have become available in recent years to correct the debilitating chronic lung congestion associated with cystic fibrosis. While the new drugs...
cystic fibrosis

A New Test to Measure the Effectiveness of CF Drugs

UNC School of Medicine researchers have developed a new laboratory model of the infection- and inflammation-plagued airways of cystic fibrosis (CF) patients. The model,...
cystic fibrosis

IUPUI Microbiologists Uncover Clues to Clustering of Lethal Bacteria in CF...

Individuals with cystic fibrosis, or CF, have a high risk of chronic pneumonia because the thick, sticky mucus that builds up in their lungs...
Cystic fibrosis

Cystic Fibrosis Scientists Discover Abnormal Response to Lung Infections

“For a very long time, there has been discussion about whether cystic fibrosis was a bacteria-infection problem, an inflammation problem, or an immune system...
antibiotic

How the Microbiome Could Tackle Antibiotic Resistant Infections in the Lungs

Miriam Moffatt, Professor of Respiratory Genetics at the National Heart and Lung Institute at Imperial College London, presented her work to shed some light...
Cystic fibrosis

The Mechanism of Mucus: UNC Discovery Could Lead to Better Cystic...

People with cystic fibrosis (CF) suffer repeated lung infections because their airway mucus is too thick and sticky to keep bacteria, viruses, and other...
chronic bacterial infections

New Strategies to Treat Chronic Bacterial Infections Pioneered at Diamond Light...

University of Southampton biological scientists, working with colleagues at the Diamond Light Source synchrotron in Oxfordshire, have gained new insight into tackling chronic bacterial...
pneumonia

Detection of Pneumonia Through Exhaled Breath

Chronic lung infections caused by the bacterium Pseudomonas aeruginosa are responsible for the majority of illnesses and deaths among CF patients. Therefore, it is important to...
Infectious Biofilms

Protein Disrupts Infectious Biofilms

Many infectious pathogens are difficult to treat because they develop into biofilms, layers of metabolically active but slowly growing bacteria embedded in a protective...
cystic fibrosis

Multi-drug Resistant Infection Spreading Globally among Cystic Fibrosis Patients

Our research should provide a degree of hope: now that we know the extent of the problem and are beginning to understand how the...
Infections

MiPACT Reveals Infections in Plain View

Cystic fibrosis (CF) is a genetic disorder in which chronic accumulations of thick mucus, called sputum, can trap bacteria in the lungs and cause...
cystic fibrosis

Low-cost Sensor for Cystic Fibrosis Diagnosis Based on Citrate

Penn State biomaterials scientists have developed a new, inexpensive method for detecting salt concentrations in sweat or other bodily fluids. The fluorescent sensor, derived...
cystic fibrosis

Study Reveals New Clues to Cystic Fibrosis ‘Gender Gap’

A research team led by structural biologists from Vanderbilt University has come up with the first detailed molecular explanation for a factor that may...