Saturday, August 17, 2019
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dietary guidelines

Update Dietary Guidelines to Save People and Planet, Scientists Urge

Well-balanced and predominantly plant-based diets can lead to improved nutrient levels, reduce premature deaths from chronic diseases by more than 20%, and lower greenhouse...
Vitamin D deficiency

Vitamin D Deficiency Affects Many Pregnant Women

One in three pregnant women has a vitamin D deficiency at the end of her pregnancy, a study recently published in PLOS ONE has...
viral infection

Against the Clock: Uncovering the First 30 Minutes of Viral Infection

For a virus attacking a cell, timing is everything. In order to take hold, these invaders must act efficiently, avoiding immune detection and remaining...
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E-Cig Use Increases Risk of Beginning Tobacco Cigarette Use in Young...

Young adults who use electronic cigarettes are more than four times as likely to begin smoking tobacco cigarettes within 18 months as their peers...
climate change

New Research Provides Maps of Climate Change Opinions by Political Party

A new study published in the journal Climatic Change finds substantial differences in the climate change views of both Republicans and Democrats across U.S....
nature

New Report Raises Alarm at Vanishing Wealth of Nature

New research from a team of Oxford economists launched at the World Forum on Natural Capital in Edinburgh today shows that governments' Ministries of Finance...
astrocytes

Star-shaped Brain Cells Orchestrate Neural Connections

Brains are made of more than a tangled net of neurons. Star-like cells called astrocytes diligently fill in the gaps between neural nets, each...
software code

Study Finds Auto-Fix Tool Gets More Programmers to Upgrade Code

Failure to make necessary upgrades to software code can have dire consequences, such as the major data breach at Equifax. A recent study finds...
microparticles

Study Shows How Rough Microparticles Can Cause Big Problems

New research from North Carolina State University, MIT and the University of Michigan finds that the surface texture of microparticles in a liquid suspension...
sperm, brain tumours, Common drugs, diabetes, chronic wounds, magnetism, intestinal tumours, molecular scissors, disease, genetic, immune cells, drug development, Diabetes, Antibiotic, hydrogen generation, chronic obstructive pulmonary disease, malaria, photosynthesis, kidney failure, Brain tumours, mental health, blood cancer, cancer, dementia, cancer treatment, antibiotic resistance, blood vessel leakage, quantum simulations, atrial fibrillation, batteries, goiter treatment, terahertz radiation, organic materials , Guild of European Research Intensive Universities, gene copies, social anxiety, blue light screens, ‘Our hope is that these findings will make it possible to discover a way to selectively inhibit the TGF-beta signals that stimulate tumour development without knocking out the signals that inhibit tumour development, and that this can eventually be used in the fight against cancer,’ says Eleftheria Vasilaki, postdoctoral researcher at Ludwig Institute for Cancer Research at Uppsala University and lead author of the study. TGF-beta regulates cell growth and specialisation, in particular during foetal development. In the context of tumour development, TGF-beta has a complicated role. Initially, it inhibits tumour formation because it inhibits cell division and stimulates cell death. At a late stage of tumour development, however, TGF-beta stimulates proliferation and metastasis of tumour cells and thereby accelerates tumour formation. TGF-beta’s signalling mechanisms and role in tumour development have been studied at the Ludwig Institute for Cancer Research at Uppsala University for the past 30 years. Recent discoveries at the Institute, now published in the current study in Science Signaling, explain part of the mechanism by which TGF-beta switches from suppressing to enhancing tumour development. Uppsala researchers, in collaboration with a Japanese research team, discovered that TGF-beta along with the oncoprotein Ras, which is often activated in tumours, affects members of the p53 family. The p53 protein plays a key role in regulating tumour development and is often altered – mutated – in tumours. TGF-beta and Ras suppress the effect of mutated p53, thereby enhancing the effect of another member of the p53 family, namely delta-Np63, which in turn stimulates tumour development and metastasis.

Mechanism Behind ‘DNA Scissor’ CRIPSR-Cas9 Further Revealed

In less than a decade, CRISPR-Cas9 has revolutionised biological research. Cas9 makes it possible, for specific purposes, to correct or modify (‘edit’) essentially any...
driving speed

Study Finds Driving Speed Affected When a Driver’s Mind ‘Wanders’

Research from North Carolina State University finds that driving speed fluctuates more when a driver’s mind wanders from focusing on the act of driving...
nuclear waste

IU Discovery Could Reduce Nuclear Waste with Improved Method to Chemically...

A discovery by Indiana University researchers could advance the long-term storage of nuclear waste, an increasingly burdensome and costly task for the public and...
Health Insurance

Does Health Insurance Status Affect Childhood Cancer Survival?

Privately insured children and those with Medicaid at the time of a cancer diagnosis experience largely similar survival trends, with slight evidence for an...
Psoriasis

Severity of Psoriasis Linked to Increased Risk of Death

The more the surface area of the body is covered by psoriasis, the greater the risk of death for the patient suffering from the...
plasticity

Scientists Restore Youthful Plasticity to the Brains of Adult Mice

Like much of the rest of the body, the brain loses flexibility with age, impacting the ability to learn, remember and adapt. Now, scientists...
warming

Earth Likely to Warm More than 2 Degrees This Century

Warming of the planet by 2 degrees Celsius is often seen as a “tipping point” that people should try to avoid by limiting greenhouse...
climate change

Extreme Weather Conditions and Climate Change Account for 40% of Global...

JRC scientists studied the relative importance of heat stress and drought on wheat yields between 1980 and 2010. They developed a new Combined Stress...
binge-eating

Optic Probes Shed Light on Binge-eating

Activating neurons in an area of the brain not previously associated with feeding can produce binge-eating behavior in mice, a new Yale study finds.When...
global warming

Varied Increases in Extreme Rainfall with Global Warming

A new study by researchers from MIT and the Swiss Federal Institute of Technology in Zurich shows that the most extreme rain events in...
technology

Technology Doesn’t Have to Be a Headache

Humans have a love-hate relationship with technology.We can't keep our hands off our phones, but we feel overwhelmed by our photo collections. We are...