Wednesday, September 18, 2019
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protein UHRF1

New Puzzle Piece Found: How Does uhrf1 Regulate Gene Activity?

Epigenetic changes often play an important role in cancers, because they cause the genetic material to be read incorrectly at certain points. Particularly critical are...
perovskite silicon tandem solar cells

New Records for Perovskite Silicon Tandem Solar Cells Through Improved Light...

Using microstructured layers, an HZB team was able to increase the efficiency of perovskite silicon tandem solar cells to currently 25.5 percent, the highest...
blue phosphorus

Blue Phosphorus – Mapped and Measured for the First Time

Until recently, the existence of "blue" phosphorus was pure theory: Now an HZB team was able to examine samples of blue phosphorus at BESSY...
graphene

Graphene Enables Clock Rates in the Terahertz Range

Graphene – an ultrathin material consisting of a single layer of interlinked carbon atoms – is considered a promising candidate for the nanoelectronics of...
Human adenoviruses

Adenovirus Hijacks Cellular Garbage Disposal

Human adenoviruses (HADV) can take control of cellular waste disposal and reprogram it to their advantage. As researchers at the Helmholtz Zentrum München report in...
encapsulins

Artificial Cell Compartments as a Molecular Workshop

How do you give cells new properties without hindering their metabolism? A team from the Helmholtz Zentrum München and the Technische Universität München (TUM) has...
mathematical analysis

Mathematical Model Identifies Differences Between Individual Cells

"Single cell data have revolutionized our understanding of many biological processes in recent years," explains Dr. Jan Hasenauer, head of the Data-driven Computational Modelling...
lung damage

New Approaches to Toxicology

Inhalation of toxic substances can result in considerable damage to the airways and the lungs. Such deleterious compounds, which include reactive oxygen species, are...
immune system

Modulating Immune Responses

The protein Roquin plays a key role in the regulation of immune reactions. LMU researchers have now uncovered details of the mechanism by which...
placenta

How Stem Cells Form the Placenta

Trophoblasts are cells that form the outer layer of a blastocyst*, which attaches itself to the wall of the uterus. In humans, trophoblasts are...
sensor molecule

Visible Signals from Brain and Heart

Key processes in the body are controlled by the concentration of calcium in and around cells. A team from the Technical University of Munich...
Antibodies

Computer Analysis Fills Gaps in Antibody Blueprint

Antibodies defend our bodies against intruders. These molecules consist of proteins with attached sugars. However, the blueprint directing the processing of these sugars on...
Cell death blocker

New BMBF Project: Cell Death Blocker Against Neurodegeneration and Dementia

With the VIP+ programme, the Federal Ministry of Education and Research (BMBF) strives to close the gap between basic research and possible translational applications....
metabolism

Novel Histone Modifications Couple Metabolism to Gene Activity

DNA is wrapped around proteins called histones, which serve to package the DNA inside the cell nucleus and play an important role in regulating...
breast cancer

How Obesity Promotes Breast Cancer

Obesity leads to the release of cytokines into the bloodstream which impact the metabolism of breast cancer cells, making them more aggressive as a...
Restless Legs Syndrome

Restless Legs Syndrome Study Identifies 13 New Genetic Risk Variants

As many as one in ten people of European ancestry is affected by restless legs syndrome, in which sufferers feel an overwhelming urge to...
cardiovascular disease

Study of Transplanted Hearts Reveals Risk Gene for Cardiovascular Disease

We know of many genes with variants that make us particularly prone to cardiovascular disease. But there are gaps in our knowledge. It is...
cancer drug

Cancer Drug Stimulates Tripolar Mode of Mitosis

Taxane-based radiochemotherapy* is widely used in the treatment of various locally advanced cancers – including non-small-cell lung carcinoma (NSCLC). Taxanes have two effects: they...
immune cells

Immune Cells Help Fat Deal with Environmental Challenges

The number of obese people as well as those suffering from type 2 diabetes is increasing worldwide. Both disorders are associated with metabolic changes...
heat generation

Plan B for Heat Generation

Brown adipose tissue is found in almost all mammals, including humans. Its cells produce heat by oxidizing sugars and fatty acids. The thermogenic protein...